Four color process is like magic. You take four screens, pull some ink, and suddenly you have a full color image on a t-shirt. It is one of the most efficient ways to tackle complex, photographic designs using a limited number of screens. But there is a downside that every printer eventually hits: the CMYK color gamut. If your design has bright, neon, or fluorescent colors, standard CMYK screen printing often falls flat. That lime green or hot pink just won't pop the way it does on your monitor.
If your green is looking more like mud than neon, you don't need to scrap the job or start over with a dozen spot colors. You just need a highlight channel. Adding one extra screen to your setup is the scrappy, pro-level trick that turns a "good" print into a "wow" print. This extra step bridges the gap between traditional process printing and high-end retail results.
Why CMYK Sometimes Struggles

To understand why we need a highlight, we have to look at how ink works. Process inks are naturally transparent. They rely on the white of the shirt (or a white base) and the overlapping of Cyan, Magenta, and Yellow to create secondary colors. While this is great for skin tones and natural landscapes, it has physical limits. Fluorescent colors and high-saturation neons exist "outside" the standard CMYK gamut. No matter how much Cyan and Yellow you mix, you will never achieve a true neon green.Â
RELATED: How to Screen Print Full Color Images with CMYK Process
Create the Highlight in Photoshop

You don't need a math degree to separate a highlight color. Most of the work happens in your digital art department before you ever burn your aluminum screens. Open your design in Photoshop and follow these steps to pull that extra color:
- Select Color Range: Go to your CMYK channels and open the Color Range tool. This allows you to target specific color data across all active channels.
- Sample Your Color: Use the eyedropper to select the specific color that’s looking dull, like that stubborn green.
- Invert and Refine: Since you are creating a film positive for CMYK screen printing, you need to invert the selection so the ink goes where the color is strongest. Use the "Fuzziness" slider to dial in the transition. You want to select the core of the green without grabbing the surrounding yellow or cyan halftones.
- Save as a Spot Channel: Save the selection and name it something clear, like "HL Green." Double click the channel, set it as a spot color, and load your specific ink color so you can see how it looks in the preview. This gives you a digital proof of how that extra "punch" will affect the final design.
Pick the Right Ink and Consistency

For the foundation of this print, we recommend using the Avient ASI 4 Color Process Plastisol Ink Set. These inks are engineered for high-speed production and consistent color reproduction. However, to get that specific text to pop, we grabbed Wilflex Epic Rio Electric Green.
There is a catch: highlight inks are usually "Ready-For-Use (RFU)" and are much thicker than transparent process inks. If you print a thick, opaque green over thin CMYK, it’s going to look like a patch stuck on top of a shirt, and the "hand" or feel of the print will be uneven. To fix this, you need to match the consistency of your equipment and inks.

We use Wilflex Fashion Soft at about 50% to reduce the ink. This makes the highlight color flow smoothly and gives it the transparency needed to blend into the rest of the print. If you don't have Fashion Soft, a halftone base works too, but Fashion Soft is the preferred way to maintain a soft feel on the garment. By reducing the ink, you allow the highlight to sit "in" the print rather than "on" the print. Using a digital scale ensures your mixing ratios are repeatable for future jobs.
RELATED: HOW TO SCREEN PRINT CMYK: BEST SETTINGS FOR AVIENT ASI INKS
Dialing in Your Print Order

In screen printing, the order of your screens changes everything. When adding a highlight to your CMYK screen printing run, you have two ways to play it based on the visual goal:
The Standard Way (Last in Order): Print your CMYK (Yellow, Magenta, Cyan, Black) and hit the highlight last. This gives you the maximum punch and vibrance because the spot color is the final layer. It creates a crisp, bright focal point that is hard to miss.
The Natural Way (First in Order): If the highlight feels too aggressive or looks "stuck on," try moving it to the beginning of the print order. When you print the other process colors on top, it "steps on" the highlight. This integrates the color more naturally into the design while still keeping that extra pop that process inks alone can't provide. In many cases, this creates a more retail-ready, blended look.
When Is It Too Much?

Adding one or two highlights is a great way to save a CMYK job and keep your screen count low. But if you find yourself adding three or four highlight screens, you’ve moved past the territory of CMYK. At that point, you are essentially doing a simulated process print.
RELATED: Everything You NEED TO KNOW to Print Sim Process
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If the design is that complex, it is often better to separate it for simulated process from the start. This allows you to control every shade with specific spot colors rather than relying on the blending of CMYK. Simulated process requires more screens but offers more control on press for high-volume jobs. However, for many shops, the "CMYK plus a highlight" method is the perfect middle ground for efficiency and quality.
One extra screen is often all it takes to turn a "good" print into a "wow" print, but having great artwork that's ready to print is a must. If you want to dive deeper into these separation techniques and master the art of the "wow" print, check out our Advanced Photoshop for Screen Printing online course. By understanding how art & separations impact printing on press, you can create amazing prints with confidence.Â
Ready to Level Up Your CMYK Prints?
Having the right inks and bases is half the battle. Explore our collection of Avient Specialty Inks and ink additives to ensure your next job pops. Want to advance you knowledge of Color Separations? Take our Advanced Photoshop course today!